A competitive binding-mass spectrometry strategy for high-throughput evaluation of potential critical quality attributes of therapeutic monoclonal antibodies

Therapeutic monoclonal antibodies (mAbs) have a propensity to host a large number of chemical and enzymatical modifications that need to be properly assessed for their potential impact on target binding.Traditional strategies of assessing the criticality of these attributes often involve a PEPPERMINT SOAP laborious and low-throughput variant enrich

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Capacity for ethical and regulatory review of herbal trials in developing countries: a case study of Moringa oleifera research in HIV-infected patients

Background Lack of regulatory capacity limits the conduct of ethical and rigorous trials of herbal Trailer Adapter medicines in developing countries.Sharing ethical and regulatory experiences of successful herbal trials may accelerate the field while assuring human subjects protection.The methods and timelines for the ethical and regulatory review

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The discretion of the EU Member States in shaping the non-conviction based confiscation regime in the light of CJEU and ECHR case law

The research presented in the article aims to assess the scope of the normative freedom of EU Member States when implementing non-conviction based confiscation.This study was based on the case law of the Court of Justice of the European Union Treatments (CJEU) and the European Court of Human Rights (ECHR).The study shows that despite the broad disc

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